系统.从Biztalk调用wcf服务时出现超时异常

我得到如下所示的异常。BizTalk能够在负载非常轻的情况下调用该服务。但是，一旦我增加了负载，并且要传输的消息数量也增加了，过了一段时间后，对于所有对该服务的调用，我都会收到此消息。

Event Type: Error
Event Source: BizTalk Server 2006
Event Category: (1)
Event ID: 5799
Date:  11/21/2011
Time:  12:55:38 PM
User:  N/A
Computer: CLBIZBTS07S
Description:
The description for Event ID ( 5799 ) in Source ( BizTalk Server 2006 ) cannot be found. The local computer may not have the necessary registry information or message DLL files to display messages from a 
remote computer. You may be able to use the /AUXSOURCE= flag to retrieve this description; see Help and Support for details. The following information is part of the event: sndManageServiceEndPoint_WCF, 
http://service.com:8100/ManageService.svc/ws, The adapter failed to transmit message going to send port "sndManageServiceEndPoint_WCF" with URL "http://service.com:8100/ManageService.svc/ws". It will be 
retransmitted after the retry interval specified for this Send Port. Details:"System.TimeoutException: Client is unable to finish the security negotiation within the configured timeout (00:01:00).  The 
current negotiation leg is 3 (00:00:20.6239920).   ---> System.TimeoutException: The request channel timed out attempting to send after 00:00:20.6239920. Increase the timeout value passed to the call to 
Request or increase the SendTimeout value on the Binding. The time allotted to this operation may have been a portion of a longer timeout. ---> System.TimeoutException: The HTTP request to 
'http://service.com:8100/ManageService.svc/ws' has exceeded the allotted timeout of 00:00:20.6230000. The time allotted to this operation may have been a portion of a longer 
timeout. ---> System.Net.WebException: The operation has timed out
   at System.Net.HttpWebRequest.GetRequestStream(TransportContext& context)
   at System.Net.HttpWebRequest.GetRequestStream()
   at System.ServiceModel.Channels.HttpOutput.WebRequestHttpOutput.GetOutputStream()
   --- End of inner exception stack trace ---
   at System.ServiceModel.Channels.HttpOutput.WebRequestHttpOutput.GetOutputStream()
   at System.ServiceModel.Channels.HttpOutput.Send(TimeSpan timeout)
   at System.ServiceModel.Channels.HttpChannelFactory.HttpRequestChannel.HttpChannelRequest.SendRequest(Message message, TimeSpan timeout)
   at System.ServiceModel.Channels.RequestChannel.Request(Message message, TimeSpan timeout)
   --- End of inner exception stack trace ---
   at System.ServiceModel.Channels.RequestChannel.Request(Message message, TimeSpan timeout)
   at System.ServiceModel.Security.IssuanceTokenProviderBase`1.DoNegotiation(TimeSpan timeout)
   --- End of inner exception stack trace ---
Server stack trace: 
   at System.ServiceModel.Security.IssuanceTokenProviderBase`1.DoNegotiation(TimeSpan timeout)
   at System.ServiceModel.Security.SspiNegotiationTokenProvider.OnOpen(TimeSpan timeout)
   at System.ServiceModel.Security.WrapperSecurityCommunicationObject.OnOpen(TimeSpan timeout)
   at System.ServiceModel.Channels.CommunicationObject.Open(TimeSpan timeout)
   at System.ServiceModel.Security.SecurityUtils.OpenCommunicationObject(ICommunicationObject obj, TimeSpan timeout)
   at System.ServiceModel.Security.SymmetricSecurityProtocol.OnOpen(TimeSpan timeout)
   at System.ServiceModel.Security.WrapperSecurityCommunicationObject.OnOpen(TimeSpan timeout)
   at System.ServiceModel.Channels.CommunicationObject.Open(TimeSpan timeout)
   at System.ServiceModel.Channels.SecurityChannelFactory`1.ClientSecurityChannel`1.OnOpen(TimeSpan timeout)
   at System.ServiceModel.Channels.CommunicationObject.Open(TimeSpan timeout)
   at System.ServiceModel.Security.SecuritySessionSecurityTokenProvider.DoOperation(SecuritySessionOperation operation, EndpointAddress target, Uri via, SecurityToken currentToken, TimeSpan timeout)
   at System.ServiceModel.Security.SecuritySessionSecurityTokenProvider.GetTokenCore(TimeSpan timeout)
   at System.IdentityModel.Selectors.SecurityTokenProvider.GetToken(TimeSpan timeout)
   at System.ServiceModel.Security.SecuritySessionClientSettings`1.ClientSecuritySessionChannel.OnOpen(TimeSpan timeout)
   at System.ServiceModel.Channels.CommunicationObject.Open(TimeSpan timeout)
   at System.ServiceModel.Channels.ServiceChannel.OnOpen(TimeSpan timeout)
   at System.ServiceModel.Channels.CommunicationObject.Open(TimeSpan timeout)
Exception rethrown at [0]: 
   at System.Runtime.Remoting.Proxies.RealProxy.HandleReturnMessage(IMessage reqMsg, IMessage retMsg)
   at System.Runtime.Remoting.Proxies.RealProxy.PrivateInvoke(MessageData& msgData, Int32 type)
   at System.ServiceModel.ICommunicationObject.Open()
   at Microsoft.BizTalk.Adapter.Wcf.Runtime.WcfClient`2.GetChannel[TChannel](IBaseMessage bizTalkMessage, ChannelFactory`1& cachedFactory)
   at Microsoft.BizTalk.Adapter.Wcf.Runtime.WcfClient`2.SendMessage(IBaseMessage bizTalkMessage)". .

在服务端，我在端点设置了maxReceivedMessageSize="2147483647"在行为部分，我设置了

 <serviceThrottling
                maxConcurrentCalls="16"
                maxConcurrentInstances="2147483647"
                maxConcurrentSessions="10"/>

这两个设置没有帮助。

当我打开wcf服务的跟踪时，我看到这些类型的错误

Activity Name Process action 'http://schemas.xmlsoap.org/ws/2005/02/trust/RST/SCT/Cancel'.
Time 2011-11-22 15:03:12.5301
Level Error
Source System.ServiceModel
Process w3wp
Thread 32
Computer FRA1BSHR01S
Trace Identifier/Code http://msdn.microsoft.com/en-US/library/System.ServiceModel.Diagnostics.ThrowingException.aspx

System.ServiceModel.EndpointNotFoundException, System.ServiceModel, Version=3.0.0.0, Culture=neutral, PublicKeyToken=b77a5c561934e089
There was no channel that could accept the message with action 'http://schemas.xmlsoap.org/ws/2005/02/trust/RST/SCT/Cancel'.
System.ServiceModel.Dispatcher.ErrorBehavior.ThrowAndCatch(Exception e, Message message)
System.ServiceModel.Channels.DatagramChannelDemuxer`2.ProcessItem(TInnerItem item)
System.ServiceModel.Channels.DatagramChannelDemuxer`2.HandleReceiveResult(IAsyncResult result)
System.ServiceModel.Channels.DatagramChannelDemuxer`2.OnReceiveComplete(IAsyncResult result)
System.ServiceModel.Channels.DatagramChannelDemuxer`2.OnReceiveCompleteStatic(IAsyncResult result)
System.ServiceModel.Diagnostics.Utility.AsyncThunk.UnhandledExceptionFrame(IAsyncResult result)
System.ServiceModel.AsyncResult.Complete(Boolean completedSynchronously)
System.ServiceModel.Channels.ReplyChannel.HelpReceiveRequestAsyncResult.OnReceiveRequest(IAsyncResult result)
System.ServiceModel.Diagnostics.Utility.AsyncThunk.UnhandledExceptionFrame(IAsyncResult result)
System.ServiceModel.AsyncResult.Complete(Boolean completedSynchronously)
System.ServiceModel.Channels.InputQueue`1.AsyncQueueReader.Set(Item item)
System.ServiceModel.Channels.InputQueue`1.EnqueueAndDispatch(Item item, Boolean canDispatchOnThisThread)
System.ServiceModel.Channels.InputQueue`1.EnqueueAndDispatch(T item, ItemDequeuedCallback dequeuedCallback, Boolean canDispatchOnThisThread)
System.ServiceModel.Channels.InputQueueChannel`1.EnqueueAndDispatch(TDisposable item, ItemDequeuedCallback dequeuedCallback, Boolean canDispatchOnThisThread)
System.ServiceModel.Channels.SingletonChannelAcceptor`3.Enqueue(QueueItemType item, ItemDequeuedCallback dequeuedCallback, Boolean canDispatchOnThisThread)
System.ServiceModel.Channels.SingletonChannelAcceptor`3.Enqueue(QueueItemType item, ItemDequeuedCallback dequeuedCallback)
System.ServiceModel.Channels.HttpChannelListener.HttpContextReceived(HttpRequestContext context, ItemDequeuedCallback callback)
System.ServiceModel.Activation.HostedHttpTransportManager.HttpContextReceived(HostedHttpRequestAsyncResult result)
System.ServiceModel.Activation.HostedHttpRequestAsyncResult.BeginRequest()
System.ServiceModel.Activation.HostedHttpRequestAsyncResult.OnBeginRequest(Object state)
System.ServiceModel.Channels.IOThreadScheduler.CriticalHelper.WorkItem.Invoke2()
System.ServiceModel.Channels.IOThreadScheduler.CriticalHelper.WorkItem.Invoke()
System.ServiceModel.Channels.IOThreadScheduler.CriticalHelper.ProcessCallbacks()
System.ServiceModel.Channels.IOThreadScheduler.CriticalHelper.CompletionCallback(Object state)
System.ServiceModel.Channels.IOThreadScheduler.CriticalHelper.ScheduledOverlapped.IOCallback(UInt32 errorCode, UInt32 numBytes, NativeOverlapped* nativeOverlapped)
System.ServiceModel.Diagnostics.Utility.IOCompletionThunk.UnhandledExceptionFrame(UInt32 error, UInt32 bytesRead, NativeOverlapped* nativeOverlapped)
System.Threading._IOCompletionCallback.PerformIOCompletionCallback(UInt32 errorCode, UInt32 numBytes, NativeOverlapped* pOVERLAP)

[TraceRecord] Severity Error
TraceIdentifier http://msdn.microsoft.com/en-US/library/System.ServiceModel.Diagnostics.ThrowingException.aspx
Description Throwing an exception.
AppDomain /LM/W3SVC/1373337114/Root-4-129664654928269938