在执行当前web请求期间发生了未处理的异常

当我运行我的web应用程序时，我突然得到了这个错误：

无法加载文件或程序集'file:///C:''Users''rafael''AppData''Local''Temp''Temporary ASP。NETFiles''root''284bddf3''431c8965''App_Web_homepage.aspx cdcab7d2.vmizb1js.dll或其依赖项之一。句柄无效。(来自的异常HRESULT:0x80070006(E_HANDLE((

这是堆栈跟踪：

FileLoadException: Could not load file or assembly 'file:///C:'Users'rafael'AppData'Local'Temp'Temporary ASP.NET Files'root'284bddf3'431c8965'App_Web_homepage.aspx.cdcab7d2.vmizb1js.dll' or one of its dependencies. The handle is invalid. (Exception from HRESULT: 0x80070006 (E_HANDLE))]
   System.Reflection.RuntimeAssembly._nLoad(AssemblyName fileName, String codeBase, Evidence assemblySecurity, RuntimeAssembly locationHint, StackCrawlMark& stackMark, Boolean throwOnFileNotFound, Boolean forIntrospection, Boolean suppressSecurityChecks) +0
   System.Reflection.RuntimeAssembly.nLoad(AssemblyName fileName, String codeBase, Evidence assemblySecurity, RuntimeAssembly locationHint, StackCrawlMark& stackMark, Boolean throwOnFileNotFound, Boolean forIntrospection, Boolean suppressSecurityChecks) +39
   System.Reflection.RuntimeAssembly.InternalLoadAssemblyName(AssemblyName assemblyRef, Evidence assemblySecurity, StackCrawlMark& stackMark, Boolean forIntrospection, Boolean suppressSecurityChecks) +132
   System.Reflection.Assembly.Load(AssemblyName assemblyRef, Evidence assemblySecurity) +28
   System.CodeDom.Compiler.CompilerResults.get_CompiledAssembly() +93
   System.Web.Compilation.BuildProvider.CreateBuildResult(CompilerResults results) +60
   System.Web.Compilation.TemplateControlBuildProvider.CreateBuildResult(CompilerResults results) +36
   System.Web.Compilation.BuildProvider.GetBuildResult(CompilerResults results) +16
   System.Web.Compilation.BuildManager.CompileWebFile(VirtualPath virtualPath) +9086138
   System.Web.Compilation.BuildManager.GetVPathBuildResultInternal(VirtualPath virtualPath, Boolean noBuild, Boolean allowCrossApp, Boolean allowBuildInPrecompile, Boolean throwIfNotFound, Boolean ensureIsUpToDate) +320
   System.Web.Compilation.BuildManager.GetVPathBuildResultWithNoAssert(HttpContext context, VirtualPath virtualPath, Boolean noBuild, Boolean allowCrossApp, Boolean allowBuildInPrecompile, Boolean throwIfNotFound, Boolean ensureIsUpToDate) +111
   System.Web.Compilation.BuildManager.GetVirtualPathObjectFactory(VirtualPath virtualPath, HttpContext context, Boolean allowCrossApp, Boolean throwIfNotFound) +125
   System.Web.Compilation.BuildManager.CreateInstanceFromVirtualPath(VirtualPath virtualPath, Type requiredBaseType, HttpContext context, Boolean allowCrossApp) +52
   System.Web.UI.PageHandlerFactory.GetHandlerHelper(HttpContext context, String requestType, VirtualPath virtualPath, String physicalPath) +31
   System.Web.UI.PageHandlerFactory.System.Web.IHttpHandlerFactory2.GetHandler(HttpContext context, String requestType, VirtualPath virtualPath, String physicalPath) +40
   System.Web.HttpApplication.MapHttpHandler(HttpContext context, String requestType, VirtualPath path, String pathTranslated, Boolean useAppConfig) +167
   System.Web.HttpServerUtility.Execute(String path, TextWriter writer, Boolean preserveForm) +517
[HttpException (0x80004005): Error executing child request for /homepage.aspx.]
   System.Web.HttpServerUtility.Execute(String path, TextWriter writer, Boolean preserveForm) +816
   System.Web.HttpServerUtility.Transfer(String path, Boolean preserveForm) +57
   System.Web.HttpServerUtility.Transfer(String path) +32
   photography.Global.Application_BeginRequest(Object sender, EventArgs e) in F:'Web Prog'my work'mcpd'gallery'photography'photography'Global.asax.cs:27
   System.Web.SyncEventExecutionStep.System.Web.HttpApplication.IExecutionStep.Execute() +148
   System.Web.HttpApplication.ExecuteStep(IExecutionStep step, Boolean& completedSynchronously) +75

我不知道这是怎么回事。因此，如果我能得到任何帮助，我将不胜感激。