Application.Run 和 Form.Load 之间会发生什么

我有一个用 VB.NET 编写的用于Framework 4.5的WinForms应用程序。我注意到应用程序的启动时间异常长(我编写的其他应用程序在启动时几乎立即启动时做更多工作，此应用程序需要>5 秒(多次启动后启动时间不会改变，所以我想这不是应用程序第一次启动期间未缓存 CLR 代码的情况。

我通过在启动期间写下时间进行了一些测试：

Module modMain
    Public MyLog As System.Text.StringBuilder
    <STAThread>
    Public Sub Main()
        MyLog = New System.Text.StringBuilder
        Application.EnableVisualStyles()
        Application.SetCompatibleTextRenderingDefault(False)
        MyLog.AppendLine("Before run: " & Date.Now.ToString & "," & Date.Now.Millisecond.ToString)
        Application.Run(frmMain)
    End Sub
End Module

Sub Main()是应用程序入口点。它运行frmMain，在那里我能控制的第一个真正的东西是Sub InitializeComponent()，由设计师生成：

<System.Diagnostics.DebuggerStepThrough()> _
Private Sub InitializeComponent()
    MyLog.AppendLine("Init Start: " & Date.Now.ToString & "," & Date.Now.Millisecond.ToString)
    'All the control initializations
    MyLog.AppendLine("Init End: " & Date.Now.ToString & "," & Date.Now.Millisecond.ToString)
End Sub

最后我到达了Form.Load活动

Private Sub frmMain_Load(sender As Object, e As EventArgs) Handles MyBase.Load
    MyLog.AppendLine("Form_Load Start: " & Date.Now.ToString & "," & Date.Now.Millisecond.ToString)
    '...
    MyLog.AppendLine("Form_Load End: " & Date.Now.ToString & "," & Date.Now.Millisecond.ToString)
End Sub

现在，MyLog 的输出如下：

Before run: 15.12.2014 19:56:47,579
Init Start: 15.12.2014 19:56:51,451
Init End: 15.12.2014 19:56:51,521
Form_Load Start: 15.12.2014 19:56:51,544
Form_Load End: 15.12.2014 19:56:51,547

您可以看到，主要暂停发生在 Application.Run() 和 Sub InitializeComponent() 之间。我从其他问题中知道，GUI 线程启动了一个消息循环，但我不知道为什么这个应用程序应该比其他应用程序慢得多。

所以我的问题是：在Application.Run和我重新获得对代码的控制点之间究竟发生了什么，我可以做些什么来加速它吗？在那里完成的工作是否与表单上的组件有任何关系？

我已经尝试使用 frmMain.ShowDialog() 而不是 Application.Run(frmMain) ，但这导致了相同的结果。我正在使用Visual Studio Express，所以很遗憾我不能使用更深入的性能分析器。

将其标记为 C# 和 VB.NET，因为非常欢迎两种语言的答案。

编辑
我做了更多的测试，包括 SLaks 答案中提出的解决方案。使用 NGEN 预编译程序集似乎没有任何明显的效果。所以我想这不是InitializeComponent代码的 JIT 编译。

然而，我注意到，在其他系统上，程序几乎是即时启动的(>快 10 倍(，即使有问题的计算机在各个方面都慢。计算机之间的区别在于操作系统：

Windows 7: Slow start
Windows 8.1: Fast start
Windows Server 2008: Fast start

这些只是更多的线索，我真的不知道它是否有助于答案。

编辑 2
在启动期间查看 ProcMon，我发现执行在以下行挂起：

"15:56:29.3547260","Electrochemical Calculator.exe","5972","CreateFile","C:'Users'Jens'Desktop'Electrochemical Calculator Barebone'Electrochemical Calculator'bin'Release'de'Electrochemical Calculator.resources.dll","PATH NOT FOUND","Desired Access: Read Attributes, Disposition: Open, Options: Open Reparse Point, Attributes: n/a, ShareMode: Read, Write, Delete, AllocationSize: n/a"
"15:56:29.3548019","Electrochemical Calculator.exe","5972","CreateFile","C:'Users'Jens'Desktop'Electrochemical Calculator Barebone'Electrochemical Calculator'bin'Release'de'Electrochemical Calculator.resources'Electrochemical Calculator.resources.dll","PATH NOT FOUND","Desired Access: Read Attributes, Disposition: Open, Options: Open Reparse Point, Attributes: n/a, ShareMode: Read, Write, Delete, AllocationSize: n/a"
"15:56:29.3548612","Electrochemical Calculator.exe","5972","CreateFile","C:'Users'Jens'Desktop'Electrochemical Calculator Barebone'Electrochemical Calculator'bin'Release'de'Electrochemical Calculator.resources.exe","PATH NOT FOUND","Desired Access: Read Attributes, Disposition: Open, Options: Open Reparse Point, Attributes: n/a, ShareMode: Read, Write, Delete, AllocationSize: n/a"
"15:56:29.3549519","Electrochemical Calculator.exe","5972","CreateFile","C:'Users'Jens'Desktop'Electrochemical Calculator Barebone'Electrochemical Calculator'bin'Release'de'Electrochemical Calculator.resources'Electrochemical Calculator.resources.exe","PATH NOT FOUND","Desired Access: Read Attributes, Disposition: Open, Options: Open Reparse Point, Attributes: n/a, ShareMode: Read, Write, Delete, AllocationSize: n/a"
"15:56:32.8796760","Electrochemical Calculator.exe","5972","CreateFile","C:'Windows'Fonts'StaticCache.dat","SUCCESS","Desired Access: Generic Read, Disposition: Open, Options: Synchronous IO Non-Alert, Non-Directory File, Attributes: n/a, ShareMode: Read, Delete, AllocationSize: n/a, OpenResult: Opened"
"15:56:32.8797088","Electrochemical Calculator.exe","5972","QueryStandardInformationFile","C:'Windows'Fonts'StaticCache.dat","SUCCESS","AllocationSize: 9,633,792, EndOfFile: 9,633,792, NumberOfLinks: 1, DeletePending: False, Directory: False"
"15:56:32.8797218","Electrochemical Calculator.exe","5972","ReadFile","C:'Windows'Fonts'StaticCache.dat","SUCCESS","Offset: 0, Length: 60, Priority: Normal"
"15:56:32.8797429","Electrochemical Calculator.exe","5972","CreateFileMapping","C:'Windows'Fonts'StaticCache.dat","FILE LOCKED WITH ONLY READERS","SyncType: SyncTypeCreateSection, PageProtection: "

该问题仅在发布版本中进一步出现，并且仅在我直接从 Windows 资源管理器启动程序时出现。调试版本会立即启动(0.3 秒，而 5-10 秒(，从 Visual Studio 启动时发布版本也是如此。